Colonic Immunopathogenesis of Clostridium difficile Infections
نویسندگان
چکیده
منابع مشابه
Extraintestinal Clostridium difficile infections.
BACKGROUND Clostridium difficile causes diarrhea that ranges from a benign, self-limiting antibiotic use-associated disease to a life-threatening pseudomembranous colitis. Clostridium difficile has rarely been isolated in extraintestinal infections. Our objective was to characterize clinical features and risk factors of these infections. METHODS Extraintestinal C. difficile infections (CDIs) w...
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Clostridium difficile infection (CDI) is now the most common definable cause of hospital-acquired and antibiotic-associated diarrhea in the United States, with the total cost of treatment estimated between 1 to 4.8 billion U.S. dollars annually (Dubberke and Olsen, 2012; DuPont, 2011; Kyne et al., 2002; Magill et al., 2014; O'Brien et al., 2007; Wilkins and Lyerly, 2003). This bacterium is resp...
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Clostridium difficile (C. difficile) infection has become one of the major hospital-associated infections in Western countries in the last two decades. However, there is limited information on the status of C. difficile infection in Chinese healthcare settings. Given the large and increasing elderly population and the well-recognized problem of over-prescribing of broad spectrum antibiotics in ...
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The detection and diagnosis of Clostridium difficile infection in pediatric populations have some unique considerations in comparison to testing in adults. The testing methodologies, including toxigenic culture, cell cytotoxicity, antigen detection, and, more recently, molecular testing, are the same in all age groups. However, limited data exist on the specific performance characteristics in c...
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BACKGROUND Clostridium difficile infections (CDI) are increasingly important in patients with antibiotic treatments, ranging from mild, self-limiting to severe, life-threatening disease. Currently, diagnostic algorithms and treatment guidelines are being adapted to novel tests and therapeutic options for recurrent CDI. METHODS A systematic literature search using the terms 'Clostridium diffic...
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ژورنال
عنوان ژورنال: Clinical and Vaccine Immunology
سال: 2014
ISSN: 1556-6811,1556-679X
DOI: 10.1128/cvi.00770-13